Chief medical officer launches push for flu jab drive

Thousands of adults missing out, warns CMO Related items fromOnMedica Cardiac experts urge patients to get flu vaccine Influenza Flu is at ‘moderate’ levels, says Public Health England Childhood vaccine uptake slumps in England
Source: OnMedica Latest News - Category: UK Health Source Type: news

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Publication date: Available online 23 March 2019Source: Computational and Structural Biotechnology JournalAuthor(s): Lifen Han, Cong Chen, Xianlin Han, Shujin Lin, Xiulan Ao, Xiao Han, Jianmin Wang, Hanhui YeAbstractInfluenza A virus are a persistent and significant threat to human health, and current vaccines do not provide sufficient protection due to antigenic drift, which allows influenza viruses to easily escape immune surveillance and antiviral drug activity. Influenza hemagglutinin (HA) is a glycoprotein needed for the entry of enveloped influenza viruses into host cells and is a potential target for anti-influenza ...
Source: Computational and Structural Biotechnology Journal - Category: Biotechnology Source Type: research
By MARC M. BEUTTLER, MD Every year at this time, you hear warnings that flu season has arrived. New data from the CDC indicates the season is far from over. So, you are urged by health authorities to get a flu shot. What you may not realize is how the flu can affect the hospitals you and your loved ones rely on for care.   In January, the large urban hospital where I am an intern faced the worst flu outbreak it has ever seen. Nearly 100 staff members tested positive for the flu. Residents assigned to back-up coverage were called to work daily to supplement the dwindling ranks of the sick. Every hospital vis...
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: Hospitals Medical Practice Marc Beuttler Vaccination Source Type: blogs
We compared three cold-adapted live attenuated influenza vaccine strains prepared by reverse genetics methods on the basis of master donor virus A/Leningrad/134/17/57 and influenza H7N9 strains A/Anhui/1/2013 and A/Shanghai/1/2013. Two strains based on A/Anhui/1/2013 differed by amino acid positions 123 and 149 in HA1 (123N/149N; 123D/149D). All strains efficiently replicated in developing chicken embryos; A/Shanghai/1/2013-based strain and A/Anhui/1/2013-123N/149N variant were characterized by reduced replication in MDCK cells. Strains based on A/Anhui/1/2013 virus agglutinated erythrocytes with α2,3- and α2,6...
Source: Bulletin of Experimental Biology and Medicine - Category: Biology Source Type: research
Publication date: April 2019Source: Current Opinion in Virology, Volume 35Author(s): Rosemary Morgan, Sabra L KleinMales/men and females/women differ in the outcome of influenza A virus (IAV) infections, vaccination, and antiviral treatments. Both sex (i.e. biological factors) and gender (i.e. sociocultural factors) can impact exposure and severity of IAV infections as well as responses and outcomes of treatments for IAV. Greater consideration of the combined effects of sex and gender in epidemiological, clinical, and animal studies of influenza pathogenesis is needed.Graphical abstract
Source: Current Opinion in Virology - Category: Virology Source Type: research
Condition:   Influenza Intervention:   Biological: FluMist Sponsors:   Stanford University;   National Institutes of Health (NIH);   National Institute of Allergy and Infectious Diseases (NIAID) Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Description of the epidemiology of influenza is needed to inform influenza vaccination policy. Here we examined influenza virus circulation in countries in the Asia-Pacific region and compared the timing of se...
Source: BMC Public Health - Category: Consumer Health News Authors: Tags: Research article Source Type: research
Authors: Chen Y, Wen Y Abstract In 2013 in mainland China, a novel avian influenza virus H7N9 began to infect humans and had aroused severe fatality in the infected humans, followed by the annual outbreaks. By methods of GIS and kriging interpolation, we get the geographical distributions. We obtain the longitudinal characteristics of these outbreaks based on statistics and diagrams. After these spatiotemporal distributions, an eco-epidemiological model is established and analyzed. In this model, the general incidence functions, the factor of fully killed infected poultry, and the virus in environment are taken int...
Source: Computational and Mathematical Methods in Medicine - Category: Statistics Tags: Comput Math Methods Med Source Type: research
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Source Type: research
AbstractThe role of viral load in the outcome of patients requiring hospital admission due to influenza is not well established. We aim to assess if there is an association between the viral load and the outcome in hospitalized patients with a confirmed influenza virus infection. A retrospective observational study including all adult patients who were hospitalized in our center with a confirmed influenza virus infection from January to May 2016. Viral load was measured by real-time reverse-transcriptase –polymerase chain reaction (rRT-PCR) cycle threshold (Ct) value on upper respiratory tract samples. Its value was ...
Source: European Journal of Clinical Microbiology and Infectious Diseases - Category: Microbiology Source Type: research
Condition:   Influenza Interventions:   Biological: MVA-NP+M1;   Drug: Saline Sponsors:   Vaccitech Limited;   Clinical Network Services (CNS) Pty Ltd Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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