Zoledronic Acid Inhibits the RhoA-mediated Amoeboid Motility of Prostate Cancer Cells.

CONCLUSION: This study demonstrates that ZA inhibits Rho-dependent amoeboid motility of PC3 cells, thus suggesting ZA as a potential therapy to impede the metastatic dissemination of PC3 cells. PMID: 30648509 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30648509?dopt=Abstract

Source: Current Cancer Drug Targets - January 15, 2019 Category: Cancer & Oncology Authors: Pietrovito L, Comito G, Parri M, Giannoni E, Chiarugi P, Taddei ML Tags: Curr Cancer Drug Targets Source Type: research