Inhibitory checkpoint receptors control CD8+ resident memory T cells to prevent skin allergy

The present study confirms the crucial role of epidermal CD8+ Trm for the recurrences of allergic contact dermatitis and highlights the contribution of immune checkpoint receptors on CD8+ Trm to prevent eczema flares upon allergen exposure.

Source: Journal of Allergy and Clinical Immunology - January 14, 2019 Category: Allergy & Immunology Authors: Pia Gamradt, L éo Laoubi, Audrey Nosbaum, Virginie Mutez, Vanina Lenief, Sophie Grande, Daniel Redoulès, Anne-Marie Schmitt, Jean-François Nicolas, Marc Vocanson Source Type: research