Mapping physical tumor microenvironment and drug delivery.

Mapping physical tumor microenvironment and drug delivery. Clin Cancer Res. 2019 Jan 10;: Authors: Nia HT, Munn LL, Jain RK Abstract The physical microenvironment of pancreatic tumors is highly abnormal, and this causes significant challenges for drug delivery through multiple mechanisms. Measurements of tissue elasticity could be used as a physical biomarker to assess aberrant drug delivery, and potentially guide stroma-targeting treatment strategies and patient stratification. PMID: 30630829 [PubMed - as supplied by publisher]
Source: Clinical Cancer Research - Category: Cancer & Oncology Authors: Tags: Clin Cancer Res Source Type: research