Hormone Therapy May Protect Against Knee Osteoarthritis Hormone Therapy May Protect Against Knee Osteoarthritis

Postmenopausal women taking hormone therapy were significantly less likely to develop symptomatic knee osteoarthritis compared with those who did not take hormone therapy, a large study has found.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Rheumatology News Source Type: news

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ConclusionsThe outcome of posterior column fractures was equal, regardless of whether these fractures were treated or not. This indicates that the three-column concept seems insufficient and gives rise to further debate on surgical strategies of posterior column fractures. The implementation of trauma mechanism-based fracture morphology in the three-column concept might be important to consummate the three-column concept as guiding tool.Level of evidence3.
Source: European Journal of Trauma and Emergency Surgery - Category: Emergency Medicine Source Type: research
In conclusion, the data indicated that miR‑31 promoted chondrocyte viability and migration by directly targeting CXCL12, which provided evidence for CXCL12 as a potential target in OA therapy. PMID: 30664157 [PubMed - as supplied by publisher]
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
Authors: Chou WY, Cheng JH, Wang CJ, Hsu SL, Chen JH, Huang CY Abstract Our study compared the effects of extracorporeal shockwave therapy (ESWT) on the subchondral bone and the articular cartilage in the treatment of early osteoarthritis (OA) of rat knee. The rats were divided into 5 groups which included Sham group, Meniscus group (ESWT applied on medial meniscus), OA group (arthrotomy and medial menisectomy (MMx) and anterior cruciate ligament transection (ACLT), T(M) group (arthrotomy and MMx and ACLT followed by ESWT on medial tibial subchondral bone) and Articular cartilage group (arthrotomy and MMx and ACLT ...
Source: International Journal of Medical Sciences - Category: Biomedical Science Tags: Int J Med Sci Source Type: research
TUESDAY, Jan. 22, 2019 -- The presence of Heberden's nodes (HNs) in finger joints may also indicate structural damage associated with knee osteoarthritis, according to a study published online Jan. 9 in Arthritis&Rheumatology. Arya...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
Analyst, 2019, Accepted Manuscript DOI: 10.1039/C8AN02014K, PaperDehui Sun, Fanlei Hu, Huanyu Gao, Zhijing Song, Wenchun Xie, Ping Wang, Lianjie Shi, Ke Wang, Yan Li, Chuncui Huang, Zhanguo Li Glycosylation is a post-translational modification essential for maintaining the structure and function of proteins. Abnormal N-glycan patterns have been found in various diseases compared to healthy controls. Decrease in terminal... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Analyst latest articles - Category: Chemistry Authors: Source Type: research
Conclusion: The proposed system is simple to use and convenient for use in ambulatory or unsupervised environments for joint measurement; however, it was shown that accuracy can be sensitive to sensor placement. Significance: This system would be beneficial for obtaining quantitative patient data or tracking functional activity in variable environments, providing clinicians with indications of how patients’ knees function during activity, potentially permitting more individualized care and recommendations.
Source: IEEE Transactions on Biomedical Engineering - Category: Biomedical Engineering Source Type: research
Corrina Towers,  51, from Great Missenden, suffered relentless fatigue, osteoarthritis in both knees and endured almost constant abdominal bloating and discomfort.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
To quantify opioid use in knee and hip osteoarthritis (OA) patients, and to estimate the proportion of opioids in the population attributable to OA patients.
Source: Osteoarthritis and Cartilage - Category: Rheumatology Authors: Source Type: research
AbstractTo investigate the association between osteoarthritis (OA) and microvascular pathology, we examined the relationship between retinal microvascular caliber and osteoarthritis of the hand and knee in an elderly population. The AGES-Reykjavik is a population-based, multidisciplinary longitudinal cohort study of aging. Retinal vessel caliber, hand osteoarthritis and total knee joint replacements due to OA were examined in 4757 individuals (mean age 76  ± 5 years; 57% female). Incident knee joint replacements during 5-year follow-up (n = 2961, mean age 75 ± 5&...
Source: Rheumatology International - Category: Rheumatology Source Type: research
ConclusionOur finite element model provides a realistic three-dimensional knee model to investigate the effects of degenerative and radial meniscal tears and resultant meniscectomy on the stress distribution of the knee. The stress was increased in meniscal tears and increased significantly when meniscectomy was performed. Increased meniscus extrusion may explain the mechanism for higher stress on the components of the knee.The translational potential of this articleMeniscal tears are the most common damage associated to the menisci, and meniscectomy is often performed to relieve the pain and instability of the knee. The r...
Source: Journal of Orthopaedic Translation - Category: Orthopaedics Source Type: research
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