Uncertainty and Coverage With Evidence Development: Does Practice Meet Theory?

In theory, a successful coverage with evidence development (CED) scheme is one that addresses the most important uncertainties in a given assessment. We investigated the following: (1) which uncertainties were present during the initial assessment of 3 Dutch CED cases, (2) how these uncertainties were integrated in the initial assessments, (3) whether CED research plans included the identified uncertainties, and (4) issues with managing uncertainty in CED research and ways forward from these issues.

Source: Value in Health - January 10, 2019 Category: International Medicine & Public Health Authors: Xavier G.L.V. Pouwels, Janneke P.C. Grutters, Jill Bindels, Bram L.T. Ramaekers, Manuela A. Joore Source Type: research