Central Nervous System Metastasis in Patients With HER2-Positive Metastatic Breast Cancer: Patient Characteristics, Treatment, and Survival From SystHERs.

Conclusions Despite advances in HER2-targeted treatments, patients with CNS metastasis continue to have a poor prognosis and impaired quality of life. Observation of CNS metastasis appears to influence HER2-targeted treatment choice. PMID: 30593513 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30593513?dopt=Abstract

Source: Clinical Cancer Research - December 28, 2018 Category: Cancer & Oncology Authors: Hurvitz SA, O'Shaughnessy J, Mason G, Yardley D, Jahanzeb M, Brufsky AM, Rugo HS, Swain SM, Kaufman PA, Tripathy D, Chu L, Li H, Antao V, Cobleigh M Tags: Clin Cancer Res Source Type: research