904: Do chronic comorbidities increase the risk of a high no-call rate in non-invasive prenatal screening?

Chronic maternal comorbidities including sickle cell disease (SCD), chronic hypertension (CHTN) and pregestational diabetes may cause vasculopathies that lead to tissue hypoxia and subsequently an increase in maternal cell necrosis which create a dilutional effect in fetal fraction on non-invasive prenatal screening (NIPS). We sought to evaluate the impact of chronic maternal comorbidities on the NIPS no-call rate. We hypothesized that chronic maternal comorbidities would increase the no-call rate for NIPS.
Source: American Journal of Obstetrics and Gynecology - Category: OBGYN Authors: Tags: Poster Session V Source Type: research