Seasonal exacerbation of eosinophilic esophagitis histologic activity in adults and children implicates role of aeroallergens

Eosinophilic esophagitis (EoE) is a chronic immune/antigen-mediated disorder characterized histologically by eosinophilic-predominant esophageal inflammation and clinically by esophageal dysfunction. The condition is diagnosed when there are at least 15 eosinophils per high-power field (eos/hpf) on esophageal biopsies following the exclusion of alternative etiologies of esophageal eosinophilia.1 –4 EoE contributes significantly to esophageal morbidity and represents the second-leading cause of esophagitis.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Source Type: research