Association of clinical outcomes in metastatic breast cancer patients with circulating tumour cell and circulating cell-free DNA

Both circulating tumour cell (CTC) and total circulating cell-free DNA (ccfDNA) predict cancer patient prognosis. However, no study has explored the prognostic value of the combined use of CTC and ccfDNA. We aimed to investigate individual and joint effects of CTC and ccfDNA on clinical outcomes of metastatic breast cancer (MBC) patients.

Source: European Journal of Cancer - December 4, 2018 Category: Cancer & Oncology Authors: Zhong Ye, Chun Wang, Shaogui Wan, Zhaomei Mu, Zhenchao Zhang, Maysa M. Abu-Khalaf, Frederick M. Fellin, Daniel P. Silver, Manish Neupane, Rebecca J. Jaslow, Saveri Bhattacharya, Theodore N. Tsangaris, Inna Chervoneva, Adam Berger, Laura Austin, Juan P. Pa Tags: Original Research Source Type: research