Complete and de novo assembly of the Leishmania braziliensis (M2904) genome.

Complete and de novo assembly of the Leishmania braziliensis (M2904) genome.
Mem Inst Oswaldo Cruz. 2018 Dec 10;114:e180438
Authors: Fuente SG, Camacho E, Peiró-Pastor R, Rastrojo A, Carrasco-Ramiro F, Aguado B, Requena/ JM
Abstract
Leishmania braziliensis is the etiological agent of American mucosal leishmaniasis, one of the most severe clinical forms of leishmaniasis. Here, we report the assembly of the L. braziliensis (M2904) genome into 35 continuous chromosomes. Also, the annotation of 8395 genes is provided. The public availability of this information will contribute to a better knowledge of this pathogen and help in the search for vaccines and novel drug targets aimed to control the disease caused by this Leishmania species.
PMID: 30540030 [PubMed - in process]

Source: Memorias do Instituto Oswaldo Cruz - December 10, 2018 Category: Infectious Diseases Authors: Fuente SG, Camacho E, Peiró-Pastor R, Rastrojo A, Carrasco-Ramiro F, Aguado B, Requena/ JM Tags: Mem Inst Oswaldo Cruz Source Type: research