Periostin Induces Kidney Fibrosis after Acute Kidney Injury via the p38 MAPK Pathway.

In conclusion, periostin promotes kidney fibrosis via the p38 MAPK pathway following acute kidney injury triggered by a hypoxic or ischemic insult. Periostin ablation may protect against CKD progression.
PMID: 30539653 [PubMed - as supplied by publisher]

Source: American Journal of Physiology. Renal Physiology - December 12, 2018 Category: Physiology Authors: An JN, Yang SH, Kim YC, Hwang JH, Park JY, Kim DK, Kim JH, Kim DW, Hur DG, Oh YK, Lim CS, Kim YS, Lee JP Tags: Am J Physiol Renal Physiol Source Type: research