Comparison of efficacy and safety of ESWL in paediatric and adolescent versus adult urolithiasis: A single center 5-year experience from a tertiary care hospital

ConclusionIn renal/upper ureteric calculi ESWL has got better efficacy, comparable safety and requires equivalent ancillary procedures in children and adolescents compared to adults.
Source: African Journal of Urology - Category: Urology & Nephrology Source Type: research

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Condition:   Urolithiasis Intervention:   Behavioral: Parents'Health-Education Handbook Sponsor:   Guohua Zeng Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Authors: Aresta C, Passeri E, Corbetta S Abstract Current primary hyperparathyroidism (PHPT) clinical presentation is asymptomatic in more than 90% of patients, while symptoms concern osteoporosis and rarely kidney stones. Here, we retrospectively investigated the prevalence of PHPT patients presenting with hypercalcemic-related symptoms (HS-PHPT) as cognitive impairment, changes in sensorium, proximal muscle weakness, nausea and vomiting, constipation, and severe dehydration, in a single center equipped with an emergency department and described their clinical features and outcome in comparison with a series of as...
Source: International Journal of Endocrinology - Category: Endocrinology Tags: Int J Endocrinol Source Type: research
Publication date: Available online 21 February 2020Source: Meta GeneAuthor(s): Zainab Nizar Jawad, Weaam AwadAbstractBackgroundSeveral genetic polymorphisms have been supposed to participate in urolithiasis progression. We investigated the association of the urokinase gene 3’-UTR and vitamin D receptor (VDR) polymorphisms with urolithiasis in an Iraqi population.MethodsTotally, 104 first kidney stone formers (63 males and 41 females), 100 recurrent stone formers (56 males and 44 females) and 127 healthy subjects (71 males and 56 females) were enrolled. The DNA was extracted from the peripheral blood; next the urokina...
Source: Meta Gene - Category: Genetics & Stem Cells Source Type: research
ConclusionThis study indicates that an aqueous leaf extract of Boldoa purpurascens may be effective in the prevention of urinary stone formation, and substantiates the traditional claim.Graphical abstract
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
Retrograde Intra Renal Surgery (RIRS) versus Percutaneous Nephrolithotomy (PCNL) for renal stones>2cm. A systematic review and meta-analysis. Minerva Urol Nefrol. 2020 Feb 19;: Authors: Barone B, Crocetto F, Vitale R, Di Domenico D, Caputo V, Romano F, De Luca L, Bada M, Imbimbo C, Prezioso D Abstract BACKGROUND: The recent advances in technology and miniaturization of endoscopic devices have permitted the use of RIRS to treat large and complicated kidney stones as first line therapy in alternative to PCNL. OBJECTIVE: Systematically review the efficacy and safety of RIRS for large renal stones o...
Source: Minerva Urologica e Nefrologica - Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research
This study aimed to investigate the renal protective effect of atorvastatin (ATV) on the kidney inflammation induced by calcium oxalate (CaOx) crystals. A cell model of cell ‐crystal interactions and a rat model of CaOx kidney stone were established. The expressions of TLR4, NF‐κB, NLRP3, and cleaved caspase‐1 in cells and rat kidney tissues were detected using Western blot, immunohistochemical, and/or immunofluorescence. The concentrations of malondialdehyde (MD A), superoxide dismutase (SOD), reactive oxygen species (ROS) in cells, and lactic acid dehydrogenase (LDH) in the culture medium were measured. The s...
Source: IUBMB Life - Category: Research Authors: Tags: RESEARCH COMMUNICATION Source Type: research
Introduction: Nephrolithiasis (NL) is a systemic and multifactorial disorder showing high prevalence and incidence in industrialized countries. The hyposodic diet is the cornerstone of NL primary and secondary prevention. The aim of this case-control study was to estimate the usual consumption of nutritional sources of salt in recurrent stone formers (RSF), treated with Extracorporeal Shock Wave Lithotripsy (ESWL), and in healthy controls without NL (C).
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - Category: Nutrition Authors: Source Type: research
Introduction: Nephrolithiasis (NL) is a systemic multifactorial disorder characterized by high recurrence rate if not properly focused and treated. Adherence to the Mediterranean diet significantly reduces the NL recurrence rate.
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - Category: Nutrition Authors: Source Type: research
We report outcomes of our initial experience with LP in 38 children from 2 months of age. Materials and Methods From June 2015 to December 2017 38 children aged 2-60 months (mean age 1.7 years) underwent LP for correction of PUJ obstruction. The mean pre operative anteroposterior diameter of the renal pelvis (APD) was 43,5mm and all patients had hydronephrosis (APD 21.4-76 mm) and obstructed curve on diuretic renogram. Anderson-Hynes pyeloplasty was the performed technique. Results are reported. Results Mean operative time was 107 minutes (70-180) with no conversion to open procedure. Pain control was needed mainly in the ...
Source: International Braz J Urol - Category: Urology & Nephrology Source Type: research
This study aimed to investigate whether Ononis spinosa L. has a litholytic effect on kidney stones with different chemical patterns.Materials and MethodsUrinary stones extracted from seven patients over 18 years of age during surgery were used as the study material. Each urinary stone was divided into two parts, one of which was left in a solution prepared with O. spinosa L. and the other constituted the control sample. The amount of calcium, phosphor and uric acid passing through each solution was detected by spectrophotometric analysis to assess its efficiency and determine whether or not the urinary stones were dissolve...
Source: Journal of Herbal Medicine - Category: Complementary Medicine Source Type: research
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