Antibiotic prescribing practices in the presence of extended-spectrum β-lactamase (ESBL) positive organisms in an adult intensive care unit in South Africa – A pilot study

ConclusionClinically it appears as if patients who received appropriate therapy according to the microbiology results showed a better clinical outcome than those with inappropriate therapy. This underlines the importance of appropriate prescribing practices in combination with co-morbid conditions. Invasive ventilatory support can be identified as a clear risk for contracting an infection due to an ESBL producing organism.
Source: Alexandria Journal of Medicine - Category: General Medicine Source Type: research

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Publication date: Available online 15 October 2019Source: Urology Case ReportsAuthor(s): C.H.F. Wong, H. Chau, C.W. Man, S.K. ChuAbstractFrom the literature, the managements for nephropulmonary fistula were variable. We would like to present our case and review the literature for the best method of care.The common features were 1) infected kidney; 2) ipsilateral lower lobe pneumonia or pleural effusion; 3) sputum and urine culture growing the same organism. Renal gaseous content may not be present on x-ray or even CT scan.The choice of management for the nephropulmonary fistula was diverse. However, conservative management...
Source: Urology Case Reports - Category: Urology & Nephrology Source Type: research
Conclusions: Implementation of an adapted aspiration risk assessment screening tool to document risk of hospital-acquired aspiration pneumonia and aspiration precautions protocol was associated with a decrease in aspiration pneumonia rates.
Source: Clinical Nurse Specialist - Category: Nursing Tags: Feature Article Source Type: research
In conclusion, D-VMP was safe and efficacious in East Asian patients, consistent with the global ALCYONE population.
Source: Annals of Hematology - Category: Hematology Source Type: research
We describe a case of a 59-year-old male with esophageal adenocarcinoma undergoing chemotherapy presenting with a right upper lobe necrotizing pneumonia secondary to B. cereus with consequent massive hemoptysis.
Source: Respiratory Medicine Case Reports - Category: Respiratory Medicine Source Type: research
Updated guidelines on community-acquired pneumonia focus on reducing inappropriate use of antibiotics and emphasize the need for more research on diagnostics and therapeutics.Medscape Medical News
Source: Medscape FamilyMedicine Headlines - Category: Primary Care Tags: Pulmonary Medicine News Source Type: news
In conclusion, to best of our knowledge these findings are the first report of isolation of 4-bromophenol and Bis (2-ethylhexyl) phthalate from genus Nocardiopsis, thus suggesting that rare actinomycetes are promising source of therapeutically important bioactive metabolites.
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
ConclusionThe draft genome sequence reported here will lay the foundation for future research on antimicrobial resistance and pathogenic mechanisms in K. quasipneumoniae subsp. quasipneumoniae and also will promote comparative analysis with genomic features among different sources of clinically important multidrug-resistant strains.
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
ConclusionIn this meta-analysis, ibrutinib was associated with significantly higher risk of infections in patients with B-cell malignancies. Occurrence of major individual subtypes was not different between groups, possibly due to inconsistent reporting across studies.
Source: Clinical Lymphoma Myeloma and Leukemia - Category: Cancer & Oncology Source Type: research
Conclusions Receipt of nerve blocks for hip fracture surgery is associated with decreased length of stay and health system costs, although small effect sizes may not reflect clinical significance for length of stay.
Source: Anesthesiology - Category: Anesthesiology Source Type: research
Publication date: Available online 15 October 2019Source: Anaesthesia &Intensive Care MedicineAuthor(s): Russell AllanAbstractCommunity-acquired pneumonia (CAP) is a common inflammatory process contained within the lung tissue in response to infection with non-hospital pathogens. Full resolution usually occurs with appropriate antimicrobial therapy. A significant proportion of patients develop severe CAP where there is failure to contain the local immune response and these patients may require admission to the intensive care unit (ICU). The CURB-65 severity score is a rapid, objective way of predicting mortality and ca...
Source: Anaesthesia and intensive care medicine - Category: Anesthesiology Source Type: research
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