[ASAP] Discovery of Clinical Candidate 2-(4-(2-((1 < italic toggle="yes" > H < /italic > -Benzo[ < italic toggle="yes" > d < /italic > ]imidazol-2-yl)thio)ethyl)piperazin-1-yl)- < italic toggle="yes" > N < /italic > -(6-methyl-2,4-bis(methylthio)pyridin-3-yl)acetamide Hydrochloride [K-604], an Aqueous-Soluble Acyl-CoA:Cholesterol < italic toggle="yes" > O < /italic > -Acyltransferase-1 Inhibitor

Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.8b01256

Source: Journal of Medicinal Chemistry - November 29, 2018 Category: Chemistry Authors: Kimiyuki Shibuya, Katsumi Kawamine, Chiyoka Ozaki, Tadaaki Ohgiya, Toshiyuki Edano, Yasunobu Yoshinaka, Yoshihiko Tsunenari Source Type: research