Etiopathogenic Role of Surfactant Protein D in the Clinical and Immunological Expression of Primary Sjögren Syndrome.

CONCLUSION: In pSS, high SP-D levels were found in patients with severe glandular involvement, hypergammaglobulinemia, leukopenia, extraglandular manifestations, and positive anti-Ro/La antibodies. The specific association between SP-D levels and pulmonary and renal involvements may have pathophysiological implications.
PMID: 25362659 [PubMed - as supplied by publisher]

Source: J Rheumatol - November 1, 2014 Category: Rheumatology Authors: Soto-Cárdenas MJ, Gandía M, Brito-Zerón P, Arias MT, Armiger N, Bové A, Bosch X, Retamozo S, Akasbi M, Pérez-De-Lis M, Gueitasi H, Kostov B, Pérez-Alvarez R, Siso-Almirall A, Lozano F, Ramos-Casals M Tags: J Rheumatol Source Type: research