Treatment of oral manifestations of toxic epidermal necrolysis with low ‐level laser therapy in a pediatric patient

AbstractDrug ‐induced reactions are complications associated with high mortality and significant morbidity. Stevens–Johnson Syndrome (SJS) and toxic epidermal necrolysis (TEN) are examples of these conditions, which are characterized by skin and mucous lesions. Here, we report a case of a 9‐year‐old girl who presented with blisters associated with an extensive vesicular rash and multiple ulcerations on the lips and oral cavity. A drug‐induced hypersensitivity reaction to antibiotics was suspected, and a diagnosis of TEN was made. The patient was managed with withdrawal of the suspected causative agent, and the oral lesions were treated with low‐level laser therapy (LLLT) and oral hygiene. This case highlights that TEN requires interdisciplinary intervention with dental assistance and follow‐up to improve symptoms, nutrition, systemic condition, and quality of life.

Source: Pediatric Dermatology - November 26, 2018 Category: Dermatology Authors: Amanda Leal Rocha, Alessandra Figueiredo De Souza, Laiz Fernandes Mendes Nunes, Nayara Dias de Souza Cunha, C élia Regina Moreira Lanza, Denise Vieira Travassos, Tarcília Aparecida da Silva Tags: CASE REPORT Source Type: research