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Recurrent terbinafine resistant Trichophyton rubrum infection in a child with congenital ichthyosis
We report the first case of terbinafine resistance in a child with recurrent T. rubrum dermatophytosis and congenital ichthyosiform erythroderma. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - January 16, 2018 Category: Dermatology Authors: Louise Sch øsler, Louise Kronborg Andersen, Maiken Cavling Arendrup, Mette Sommerlund Tags: BRIEF REPORT Source Type: research

Utility of ultrasonography in hair ‐thread tourniquet syndrome
Abstract A 2‐year‐old girl presented with a 2‐month history of an erythematous, indurated plaque with well‐defined borders on the third toe of the right foot. Bedside high‐resolution ultrasonography demonstrated a thickened epidermis overlying a hyperechoic focus within the dermis. Her clinical and sonographic presentation was in keeping with a foreign body causing hair‐thread tourniquet syndrome. The foreign body was surgically extirpated without neurovascular sequelae. Ultrasonography expedited accurate diagnosis and is a promising adjunct to clinical evaluation for radiolucent foreign bodies. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - January 16, 2018 Category: Dermatology Authors: Deshan F. Sebaratnam, Ángela Hernández‐Martín Tags: BRIEF REPORT Source Type: research

Severe ectropion in lamellar ichthyosis managed medically with oral acitretin
We report a neonate with severe, bilateral, congenital ectropion and eclabium managed using oral retinoids. Both corneas were protected with topical antibiotics and lubricating eyedrops and eye ointments. At 12‐month follow‐up, the child was doing well, with no ectropion or corneal opacity. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - January 15, 2018 Category: Dermatology Authors: Manpreet Singh, Manpreet Kaur, Ripanjeet Kaur, Shakeen Singh Tags: Case Report Source Type: research

Oxybutynin 3% gel for the treatment of primary focal hyperhidrosis in adolescents and young adults
ConclusionOxybutynin 3% gel reduced hyperhidrosis severity and improved health‐related quality of life in this small pilot study. Safety and efficacy should be further evaluated in a large, prospective, placebo‐controlled study. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - January 15, 2018 Category: Dermatology Authors: Nicholas V. Nguyen, Jane Gralla, James Abbott, Anna L. Bruckner Tags: ORIGINAL ARTICLE Source Type: research

A comprehensive next ‐generation sequencing assay for the diagnosis of epidermolysis bullosa
ConclusionsEBSEQ is a sensitive, relatively rapid, minimally invasive, comprehensive genetic assay for the diagnosis of epidermolysis bullosa. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - January 15, 2018 Category: Dermatology Authors: Anne W. Lucky, Neha Dagaonkar, Karen Lammers, Ammar Husami, Diane Kissell, Kejian Zhang Tags: Original Article Source Type: research

Use of antiviral medications in drug reaction with eosinophilia and systemic symptoms (DRESS): A case of infantile DRESS
Abstract A 3‐month‐old girl with Sturge‐Weber syndrome presented with a morbilliform rash, eosinophilia, and fulminant liver failure to our tertiary pediatric hospital. She was diagnosed with drug reaction with eosinophilia and systemic symptoms complicated by viremia and evidence of viral hepatitis on liver biopsy. We discuss the role of viral reactivation in drug reaction with eosinophilia and systemic symptoms and the relevance of antiviral therapy in management. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - January 15, 2018 Category: Dermatology Authors: Maggie L. Chow, David Kim, Sonia Kamath, David Peng, Minnelly Luu Tags: CASE REPORT Source Type: research

Incidence, outcomes, and resource use in children with Stevens ‐Johnson syndrome and toxic epidermal necrolysis
ConclusionsThe incidence of Stevens‐Johnson syndrome and toxic epidermal necrolysis in children is higher than reported in adults, and there are significant age‐based variations in incidence and outcomes across the pediatric population. Further study is needed to determine the most effective treatment strategies to reduce costs and improve outcomes in children hospitalized with severe cutaneous reactions. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - January 9, 2018 Category: Dermatology Authors: James W. Antoon, Jennifer L. Goldman, Brian Lee, Alan Schwartz Tags: ORIGINAL ARTICLE Source Type: research

Pityriasis lichenoides: Long ‐term follow‐up study
ConclusionPityriasis lichenoides is a predominantly pediatric disorder. The time course of pityriasis lichenoides chronica is significantly longer than that of pityriasis lichenoides et varioliformis acuta. Pityriasis lichenoides chronica may persist with pigmentary alterations in the absence of other signs of active inflammation. Treatment response is often limited, particularly for patients with pityriasis lichenoides chronica. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - January 9, 2018 Category: Dermatology Authors: Julie B. Zang, Sarah J. Coates, Jing Huang, Eric C. Vonderheid, Bernard A. Cohen Tags: ORIGINAL ARTICLE Source Type: research

Mood changes with methotrexate therapy for dermatologic disease
We describe two children who experienced mood changes with methotrexate treatment for lichen sclerosus with morphea overlap and psoriasis, with rapid resolution of these symptoms after methotrexate cessation. We also detail possible mechanisms underlying psychiatric changes with methotrexate therapy. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - January 9, 2018 Category: Dermatology Authors: Trisha Bhat, Carrie C. Coughlin Tags: BRIEF REPORT Source Type: research

Doing the math: A simple approach to topical timolol dosing for infantile hemangiomas
This report offers a simplified calculation of the maximum daily safe dosage as 1 drop of medication per kilogram of body weight. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - January 9, 2018 Category: Dermatology Authors: Renata Dalla Costa, Brea Prindaville, Karen Wiss Tags: PEDIATRIC DERMATOLOGY PROCEDURES AND PEARLS Source Type: research

Rapid, successful treatment of atopic dermatitis recalcitrant to topical corticosteroids
We describe the case of a young girl with a 2‐year history of atopic dermatitis resistant to triamcinolone whose condition rapidly improved with continued use of triamcinolone. Our case raises the ethical dilemma of whether physicians should base treatment plans on what patients report or what evidence on adherence suggests. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - January 4, 2018 Category: Dermatology Authors: Daniel J. Lewis, Steven R. Feldman Tags: ART AND PRACTICE OF PEDIATRIC DERMATOLOGY Source Type: research

Wound infection after inpatient pediatric skin biopsy
Abstract Punch and shave biopsies are important dermatologic procedures in the inpatient setting but have a risk of wound infection. Data on the incidence of infection in this setting are limited and conflicting. This retrospective study of 127 pediatric inpatients at two tertiary care centers who underwent biopsy demonstrated a low overall risk of infection (n = 1, 0.8%). Twenty‐five (19.7%) were neutropenic, and 51 (40.2%) were not taking systemic antibiotics at the time of biopsy; none of these patients developed a wound infection. The overall low rate of infection should reassure physicians who are balancin...
Source: Pediatric Dermatology - January 4, 2018 Category: Dermatology Authors: Hannah Song, Arash Mostaghimi, Jennifer T. Huang Tags: BRIEF REPORT Source Type: research

A rare presentation of congenital syphilis: Pemphigus syphiliticus in a newborn infant with extensive desquamation of the extremities
We present an unusual case of broad desquamation of the extremities in a newborn infant who was found to have congenital syphilis. Pemphigus syphiliticus should be considered in the differential diagnosis of neonatal bullous eruptions and erosions. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - January 4, 2018 Category: Dermatology Authors: Elizabeth A. Wang, Cindy J. Chambers, Marc Silverstein Tags: CASE REPORT Source Type: research

Approach to the jewelry aficionado
Abstract Children's and teens’ frequent use of inexpensive “costume” jewelry exposes them to a variety of contact allergens. Greater use heightens the risk of developing allergic contact dermatitis, especially in the setting of body piercings. Several clinical pearls, prevention strategies, and avoidance alternatives are provided in this article to guide clinicians and patients in the management of jewelry‐related allergic contact dermatitis. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - January 4, 2018 Category: Dermatology Authors: Lauren A. Ivey, Brittanya A. Limone, Sharon E. Jacob Tags: PEDIATRIC DERMATOLOGY PROCEDURES AND PEARLS Source Type: research

Delayed ‐type hypersensitivity to vaccine aluminum adjuvant causing subcutaneous leg mass and urticaria in a child
Abstract A 3‐year‐old girl presented with a 7‐month history of a waxing and waning left thigh mass associated with pruritus and erythema at the site of two previous DTaP‐HepB‐IPV vaccinations. Patch testing was positive to aluminum chloride, supporting a diagnosis of vaccine granuloma secondary to aluminum allergy; her symptoms had been well controlled with antihistamines and topical steroids. Injection site granulomas are a benign but potentially bothersome reaction to aluminum‐containing immunizations that can be supportively managed, and we encourage strict adherence to the recommended vaccine schedule in th...
Source: Pediatric Dermatology - January 4, 2018 Category: Dermatology Authors: Samantha C. Gordon, Diana W. Bartenstein, Shahein H. Tajmir, Johanna S. Song, Elena B. Hawryluk Tags: CASE REPORT Source Type: research

Clinical features and nail clippings in 52 children with psoriasis
ConclusionThere seems to be a correlation between some microscopic nail features in children with psoriasis and their PASI and NAPSI scores, so nail clippings from children with suspected psoriasis may help with diagnosis, especially in the presence of neutrophils, and in excluding onychomycosis. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - January 4, 2018 Category: Dermatology Authors: Marjorie Uber, V ânia O. Carvalho, Kerstin T. Abagge, Renata Robl Imoto, Betina Werner Tags: ORIGINAL ARTICLE Source Type: research

Acral pigmented Spitz nevus in a child with transepidermal migration of melanocytes: Dermoscopic and reflectance confocal microscopic features
We report a new case on the palm of a 4‐year‐old girl that demonstrated correlation between features observed on dermoscopy and reflectance confocal microscopy (RCM). Histopathology revealed a benign intraepidermal Spitz nevus with transepidermal elimination of melanocytes that showed on RCM as focal atypical bright cells concerning for malignancy. This case is one of few reports in the literature combining dermoscopy, reflectance confocal microscopy, and histology for an acral Spitz nevi, which are rarely evaluated by RCM given the thickness of the stratum corneum in acral sites. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - January 4, 2018 Category: Dermatology Authors: Christopher Iriarte, Babar Rao, Attiya Haroon, Anna Yasmine Kirkorian Tags: CASE REPORT Source Type: research

Isotretinoin ‐induced acne fulminans without systemic symptoms with concurrent exuberant granulation tissue
We report a case of isotretinoin‐induced acne fulminans without systemic symptoms with exuberant granulation tissue response that was treated successfully with topical clobetasol ointment. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - January 4, 2018 Category: Dermatology Authors: Alvin W. Li, Richard J. Antaya Tags: BRIEF REPORT Source Type: research

Potassium iodide in refractory, recurrent pediatric Sweet syndrome: Guidance in dosing and monitoring
We describe a 5‐month‐old boy with clinical and histopathologic presentation of Sweet syndrome. He responded to systemic corticosteroids, with multiple flares on tapering; potassium iodide was added, which provided complete resolution of Sweet syndrome. Potassium iodide has been used in only a few cases, and no standard dosage has been established in children. We discuss calculation of a pediatric dosage for potassium iodide in Sweet syndrome. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - January 4, 2018 Category: Dermatology Authors: Jennifer Aileen Ang Tangtatco, Nhung Ho, Aaron Drucker, Catherine Forse Tags: PEDIATRIC DERMATOLOGY PROCEDURES AND PEARLS Source Type: research

Vitiligoid variant of lichen sclerosus in young girls with darker skin types
ConclusionsThe girls presented in this series appear to have had vitiligoid lichen sclerosus, given the clinical overlap of lichen sclerosus and vitiligo affecting the anogenital region, particularly given that they did not have depigmented patches elsewhere on their body. Previous cases of vitiligoid lichen sclerosus have been reported in darker skin types, and our findings support this possible predisposition. It is important for clinicians to assess patients presenting with genital depigmentation for overlapping features of vitiligo and lichen sclerosus and determine appropriate management. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - January 4, 2018 Category: Dermatology Authors: Margaret H. Dennin, Sarah L. Stein, Adena E. Rosenblatt Tags: ORIGINAL ARTICLE Source Type: research

Pediatric psoriasis: Evolving perspectives
ConclusionPediatric psoriasis is an important immune‐mediated inflammatory skin disease with potential for significant impact on affected individuals and their caregivers. Current state‐of‐the‐art care is based primarily on experience and expert consensus, but pediatric data are accumulating and therapeutic options are rapidly evolving. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - January 4, 2018 Category: Dermatology Authors: Lawrence F. Eichenfield, Amy S. Paller, Wynnis L. Tom, Jeffrey Sugarman, Adelaide A. Hebert, Sheila Fallon Friedlander, Elaine Siegfried, Nanette Silverberg, Kelly M. Cordoro Tags: ORIGINAL ARTICLE Source Type: research

Topical 1% propranolol ointment with occlusion in treatment of pyogenic granulomas: An open ‐label study in 22 children
ConclusionTopical propranolol ointment 1% with occlusion appears to be an effective treatment for PGs in children. Early treatment was associated with a more favorable outcome. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - December 20, 2017 Category: Dermatology Authors: Iria Neri, Carlotta Baraldi, Riccardo Balestri, Bianca Maria Piraccini, Annalisa Patrizi Tags: ORIGINAL ARTICLE Source Type: research

Midline anterior neck inclusion cyst: A novel superficial congenital developmental anomaly of the neck
ConclusionWe have termed this entity midline anterior neck inclusion cyst. We believe it is a superficial developmental anomaly, probably a forme fruste of a midline fusion developmental defect, which has not to our knowledge, previously been described. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - December 20, 2017 Category: Dermatology Authors: Rabina Walsh, Jeffrey North, Kelly M. Cordoro, Ana Isabel Rodr íguez Bandera, Leonard Kristal, Ilona J. Frieden Tags: ORIGINAL ARTICLE Source Type: research

Unique presentation of transient zinc deficiency from low maternal breast milk zinc levels
We report full‐term siblings with a unique clinical presentation of polycyclic papulosquamous plaques secondary to transient zinc deficiency due to low maternal breast milk zinc levels. We present this case to highlight this unique presentation of zinc deficiency in breastfed infants. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - December 20, 2017 Category: Dermatology Authors: Tina Tang, Joseph M. Lam Tags: BRIEF REPORT Source Type: research

Association between extremity kaposiform hemangioendothelioma and lymphedema
We present a patient with a thigh kaposiform hemangioendothelioma successfully treated using a systemic corticosteroid during infancy who was diagnosed with lymphedema in the extremity 9 years later. The observation that extremity kaposiform hemangioendothelioma could possibly be associated with lymphedema has implications for the care of patients with kaposiform hemangioendothelioma. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - December 20, 2017 Category: Dermatology Authors: Dennis J. Konczyk, Jeremy A. Goss, Reid A. Maclellan, Arin K. Greene Tags: BRIEF REPORT Source Type: research

Fatal disseminated Trichosporon asahii fungemia in a child with acute lymphoblastic leukemia and a morbilliform eruption
We present the case of a 10‐year‐old boy with acute lymphoblastic leukemia who developed a diffuse, morbilliform eruption in the setting of fever and pancytopenia. He was found to have Trichosporon asahii fungemia with widespread visceral dissemination, and his condition rapidly deteriorated despite treatment. It is important to consider trichosporonosis in the evaluation of a critically ill individual with neutropena and a rash, because the initial cutaneous presentation may appear benign and delayed therapy results in death. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - December 20, 2017 Category: Dermatology Authors: Julie K. Nguyen, Megan J. Schlichte, Deborah Schady, Crystal Y. Pourciau Tags: BRIEF REPORT Source Type: research

Pediatric dermatology procedures and pearls: Multimodal revision of earlobe keloids
Abstract Keloid scars are benign proliferations of fibrous tissue and collagen that usually occur in response to cutaneous injury. Many treatment modalities have been described in the literature, with variable rates of recurrence and no clear consensus. Keloids remain a therapeutic challenge to patients and physicians alike. Herein we describe a novel technique for treating recurrent earlobe keloids in an outpatient setting with multimodal therapy including shave removal followed immediately by ablative fractional laser resurfacing (AFR) and laser‐assisted delivery (LAD) of corticosteroids. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - December 20, 2017 Category: Dermatology Authors: Tanya Greywal, Andrew C. Krakowski Tags: PEDIATRIC DERMATOLOGY PROCEDURES AND PEARLS Source Type: research

Local anesthesia in pediatric dermatologic surgery: Evaluation of a patient ‐centered approach
ConclusionSpecific measures for therapeutic pediatric patient education may be helpful in limiting discomfort, anxiety, and pain perception linked to procedures performed under local anesthesia. Further controlled studies are required to more precisely assess the benefits of specific therapeutic education measures. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - December 15, 2017 Category: Dermatology Authors: May El Hachem, Claudia Carnevale, Andrea Diociaiuti, Cristiana De Ranieri, Simona Giancristoforo, Giovanna Zambruno, Marta L. Ciofi Degli Atti Tags: ORIGINAL ARTICLE Source Type: research

Pulmonary nodules and nodular scleritis in a teenager with superficial granulomatous pyoderma gangrenosum
We present the case of a 15‐year‐old boy with pulmonary involvement and nodular scleritis associated with this unusual type of pyoderma gangrenosum and discuss its differential diagnosis. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - December 15, 2017 Category: Dermatology Authors: Francisco A. Contreras ‐Verduzco, Sara E. Espinosa‐Padilla, Luz Orozco‐Covarrubias, Adriana Alva‐Chaire, César M. Rojas‐Maruri, Marimar Sáez‐de‐Ocariz Tags: CASE REPORT Source Type: research

Holmes heart and tetralogy of Fallot in association with PHACE
We report a case of Holmes heart and three cases of tetralogy of Fallot in PHACE association. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - December 15, 2017 Category: Dermatology Authors: Caitlin M. Peterman, Keith W. Morley, Albert C. Yan, Leslie A. Castelo ‐Soccio, Marilyn G. Liang Tags: CASE REPORT Source Type: research

A prospective study of topical carteolol therapy in Chinese infants with superficial infantile hemangioma
ConclusionCarteolol is an effective, safe topical treatment for superficial IHs. Carteolol may be used to treat proliferative superficial IHs, particularly in infants younger than 6 months. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - December 15, 2017 Category: Dermatology Authors: Li ‐qiang Gan, Hua Wang, Si‐li Ni, Chun‐hua Tan Tags: ORIGINAL ARTICLE Source Type: research

Chemotherapy ‐induced eccrine squamous syringometaplasia in an infant
We report the first case of an infant developing this condition after treatment with busulfan, fludarabine, and antithymocyte globulin in preparation for bone marrow transplantation. Twenty‐eight days after transplantation, the infant developed faintly erythematous papules and plaques on the bilateral axillae, inguinal folds, and sites of adhesives. Punch biopsy revealed eccrine glands with dyskeratotic cells and focal squamous metaplasia consistent with chemotherapy‐induced eccrine squamous syringometaplasia. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - December 12, 2017 Category: Dermatology Authors: Peter G. Bittar, Megan Casady, Maria A. Selim, Neil S. Prose Tags: BRIEF REPORT Source Type: research

Retrospective review of immunocompromised children undergoing skin biopsy for suspected invasive infection: Analysis of factors predictive of invasive mold
Abstract ObjectivesCutaneous lesions are often the first marker of invasive mold infection, which can cause substantial morbidity in immunocompromised children. The purpose of this study was to describe the evaluation and outcomes of immunocompromised children who presented with findings requiring skin biopsy because of concern about invasive infection. In children who were biopsied, we sought to determine the factors predictive of invasive mold infection. MethodsA retrospective review was conducted at the Children's Hospital of Philadelphia. Patients included in the study were immunocompromised individuals younger than 26...
Source: Pediatric Dermatology - December 12, 2017 Category: Dermatology Authors: Robert J. Smith, Sarah B. Klieger, Salwa E. Sulieman, Emily Berger, James R. Treat, Brian T. Fisher Tags: ORIGINAL ARTICLE Source Type: research

Characteristics of pediatric recurrent erythema multiforme
ConclusionThis study of pediatric recurrent EM found a greater male predominance, more hospitalizations, fewer cases caused by herpes simplex virus, and a lower response to immunosuppression in children than in the general population. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - December 12, 2017 Category: Dermatology Authors: Adam Heinze, Megha Tollefson, Kristen E. Holland, Yvonne E. Chiu Tags: ORIGINAL ARTICLE Source Type: research

Internal venous anomalies in patients with a genital venous malformation
ConclusionNearly half of our patients with a focal genital venous malformation had internal venous anomalies. Physicians should suspect urogenital or gastrointestinal venous malformations in patients with a focal genital venous malformation, especially if they develop hematuria, hematochezia, or rectorrhagia. Significant mesenteric venous trunk anomalies can also occur. Because these require surgical intervention, early recognition is important. We recommend that all patients with a focal genital venous malformation undergo abdominal and pelvic ultrasound to evaluate for internal venous anomalies. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - December 12, 2017 Category: Dermatology Authors: Caitlin M. Peterman, Patricia S. Todd, Anna P. Lillis, Steven J. Fishman, Marilyn G. Liang Tags: ORIGINAL ARTICLE Source Type: research

Circadian rhythm in atopic dermatitis —Pathophysiology and implications for chronotherapy
Abstract Circadian rhythm is a biological clock that controls a wide range of physiological functions throughout the body, including various skin functions. A 24‐h diurnal cycle, governed by an endogenous clock in the brain, largely controls cutaneous diurnal rhythm, which external factors, including temperature, humidity, diet, and stress, also modulate locally. Circadian rhythm influences cutaneous blood flow and properties of skin barrier function, such as transepidermal water loss and capacitance, and has important implications in atopic dermatitis (AD). This review explores how aberrations in circadian rhythm may pl...
Source: Pediatric Dermatology - December 12, 2017 Category: Dermatology Authors: Alexandra R. Vaughn, Ashley K. Clark, Raja K. Sivamani, Vivian Y. Shi Tags: ART AND PRACTICE OF PEDIATRIC DERMATOLOGY Source Type: research

A case of keratosis circumscripta in a Chinese boy
We report here a case of keratosis circumscripta in a 13‐year‐old Chinese boy who presented with pruritic follicular keratotic rashes below both knees. This case indicates that keratosis circumscripta may not occur only in individuals of African descent. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - December 12, 2017 Category: Dermatology Authors: He Zhang, Wei Deng, Xiaoyan Zhang Tags: CASE REPORT Source Type: research

Pernio as the presenting sign of blast crisis in acute lymphoblastic leukemia
Abstract A previously healthy 5‐year‐old girl presented with acute onset of blue toes and red spots on the nose and fingers. The striking nature of these lesions, along with the finding of submandibular lymphadenopathy, prompted further evaluation. Laboratory findings were remarkable for anemia, high transaminase levels, and high blast count. Histopathologic findings were consistent with early pernio. Further examination revealed acute B‐cell lymphoblastic leukemia. Treatment of the leukemia led to resolution of the pernio. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - December 12, 2017 Category: Dermatology Authors: Kelly K. Park, Bailey Tayebi, Lily Uihlein, Jodi Speiser, Adnan Mir, Pedram Gerami, Anthony Mancini, Wendy Kim Tags: BRIEF REPORT Source Type: research

Acral ‐accentuated exanthem in an infant with parechovirus meningitis
We report a case of an infant who had presented with fever and an acral‐accentuated rash, for which his cerebrospinal fluid returned positive for parechovirus. He was treated symptomatically and discharged well, with no long‐term complications. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - December 4, 2017 Category: Dermatology Authors: Dawn Lee, Sin Wee Loh, Juliet Tan, Jinho Chong Tags: CASE REPORT Source Type: research

Excellent response to ustekinumab in a 9 ‐year‐old girl with severe psoriasis
We report the case of a 9‐year‐old girl with severe plaque psoriasis refractory to multiple topical and systemic therapies. Physical examination revealed extensive, erythematous plaques with overlying thick scales that covered more than 80% of her body surface area, which included the face, scalp, trunk, and limbs. Because of the severity of the disease and lack of treatment response to other systemic therapies, she was treated with ustekinumab. Three weeks after ustekinumab was initiated, her psoriatic lesions fully cleared. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - December 4, 2017 Category: Dermatology Authors: Reina M. Gonz ález‐Barreto, Nicole M. Rochet, Oscar W. Nevares‐Pomales, Francisco Colón‐Fontanez Tags: BRIEF REPORT Source Type: research

Discordance of pediatric morphea treatment by pediatric dermatologists
ConclusionThe survey found large variation in how pediatric dermatologists treat pediatric morphea. Consensus treatment guidelines developed by pediatric dermatologists and pediatric rheumatologists are urgently needed regarding the efficacy of therapies for pediatric morphea. Prospective studies of treatment efficacy in pediatric morphea are urgently needed as well. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - November 22, 2017 Category: Dermatology Authors: Megha M. Tollefson, Yvonne E. Chiu, Heather A. Brandling ‐Bennett, Elena Pope Tags: ORIGINAL ARTICLE Source Type: research

Erythromelanosis follicularis faciei et colli: A clinicoepidemiologic study
We describe 25 cases of erythromelanosis follicularis faciei et colli from India. The male:female ratio was 5.25:1 and the average age of onset was 12.3 years. The cheeks, preauricular area, and submandibular region were the sites most commonly affected. Keratosis pilaris was seen in 22 (88%) of the patients. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - November 21, 2017 Category: Dermatology Authors: Tasleem Arif, Mohammad Adil, Syed Suhail Amin, Mohammad Tahseen, Konchok Dorjay, Mohd Mohtashim, Manu Singh, Roopal Bansal, Dinesh Raj Tags: BRIEF REPORT Source Type: research

Urticarial vasculitis after meningococcal serogroup B vaccine in a 6 ‐year‐old girl
Abstract The first vaccine that shows significant potential in providing broad coverage against serogroup B meningococcal disease has recently been approved. Because of its newness, potential adverse events need to be reported. Here we report a case of urticarial vasculitis, a rare disease in children, in probable relationship with the novel vaccine. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - November 21, 2017 Category: Dermatology Authors: Virginia Velasco ‐Tamariz, Marta Prieto‐Barrios, Fátima Tous‐Romero, Sara Isabel Palencia‐Pérez, Concepción Postigo‐Llorente Tags: BRIEF REPORT Source Type: research

Juvenile mycosis fungoides with large ‐cell transformation: Successful treatment with psoralen with ultraviolet A light, interferon‐alfa, and localized radiation
We present the first case of a child with almost complete remission of his mycosis fungoides with large‐cell transformation shortly after administration of psoralen plus ultraviolet A, interferon‐alfa, and localized radiation. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - November 21, 2017 Category: Dermatology Authors: Warren H. Chan, Daniel J. Lewis, Tiffany Hinojosa, Jonathan L. Curry, Madeleine Duvic Tags: CASE REPORT Source Type: research

Demographic characteristics of teenage boys with horizontal striae distensae of the lower back
ConclusionOur results indicate that horizontal striae distensae of the lower back in adolescent boys is associated with a rapid growth spurt, tall stature, and family history of striae distensae. There is no association between this type of striae distensae and any chronic medical condition, bacterial infection, or exogenous steroid use. Thus a careful review of systems and counseling without further medical testing is reasonable management. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - November 21, 2017 Category: Dermatology Authors: Emily Boozalis, Anna L. Grossberg, Katherine B. Puttgen, Candrice R. Heath, Bernard A. Cohen Tags: ORIGINAL ARTICLE Source Type: research

Severe Stevens ‐Johnson syndrome/toxic epidermal necrolysis overlap syndrome—beyond skin involvement
We describe the case of an 8‐year‐old girl who developed severe SJS/TEN overlap syndrome (25% of her body surface area was affected) complicated by pancreatitis and bronchiolitis obliterans. These rare complications emphasize the need for careful, intensive monitoring of possible complications and an interdisciplinary team approach to provide optimal treatment and follow‐up. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - November 21, 2017 Category: Dermatology Authors: Tiago Milheiro Silva, Jo ão Farela Neves, Ana Casimiro, Luís Varandas, Catarina Gouveia Tags: CASE REPORT Source Type: research

Prevalence of sun protection behaviors in Hispanic youth residing in a high ultraviolet light environment
Abstract Although rates of late‐stage melanoma are rising in Hispanics, particularly those living in high ultraviolet light environments, little is known about the prevalence of sun protective behaviors in Hispanic children. We analyzed baseline data including frequency of sunburn, sun protective behaviors, level of U.S. acculturation, and skin phototype from a cross‐sectional survey of 2003 Hispanic elementary school children in Los Angeles, California, who participated in a skin cancer prevention intervention. Although the Hispanic children reported frequently engaging in some sun protective behaviors, they also had ...
Source: Pediatric Dermatology - November 21, 2017 Category: Dermatology Authors: Lisa Altieri, Kimberly A. Miller, Jimi Huh, David H. Peng, Jennifer B. Unger, Jean L. Richardson, Martin W. Allen, Myles Cockburn Tags: BRIEF REPORT Source Type: research

Bleomycin ‐induced flagellate erythema after venous malformation sclerosis—Case report and brief review
We report the case of a boy with a left foot venous malformation who developed this skin rash after two sessions of bleomycin intralesional injection. We discuss the mechanism and characteristics of this reaction to bleomycin, which is usually benign and self‐limited. We conclude that, although rare, flagellate pigmentation can occur when bleomycin is used as a sclerosant in children. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - November 21, 2017 Category: Dermatology Authors: Cristina Pinto, Concepci ón Lorca‐Garcia, Beatriz Berenguer, Maria Elena De Tomás Palacios Tags: CASE REPORT Source Type: research

Considerations in surgical management of a Buschke –Lowenstein tumor in Netherton syndrome: A case report
This report describes a pediatric case of a Buschke–Lowenstein tumor of the natal cleft in a patient with Netherton syndrome that had failed to respond to medical management. We reviewed the literature for previous cases of surgery in individuals with Netherton syndrome using MEDLINE and PubMed searches. Our patient underwent surgery to remove the lesion without complication. Using conventional dressings and topical negative‐pressure therapy, the wound was managed and healed within a reasonable time frame despite the underlying skin condition. This case indicates that surgery and topical negative‐pressure therapy...
Source: Pediatric Dermatology - November 16, 2017 Category: Dermatology Authors: Rosalind Ashton, Jamil Moledina, Branavan Sivakumar, Jemima E. Mellerio, Anna E. Martinez Tags: CASE REPORT Source Type: research

Fibroadipose vascular anomaly treated with sirolimus: Successful outcome in two patients
We report two cases of FAVA in which treatment with sirolimus produced rapid, dramatic improvement in pain and quality of life. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - November 16, 2017 Category: Dermatology Authors: Jonathan Erickson, William McAuliffe, Lewis Blennerhassett, Anne Halbert Tags: CASE REPORT Source Type: research