Partial versus maximal forced exhalations in COPD: Enhanced signal detection for novel therapies

Conclusions The use of PF800 increased detection of a BDR in COPD compared to FEV1 alone and may reflect small airway responses. The PEFV maneuver is simple, repeatable and may avoid some of the theoretical disadvantages of FEV1. The role of PF800 for evaluating novel anti-inflammatory agents remains to be determined.
Source: Pulmonary Pharmacology and Therapeutics - Category: Respiratory Medicine Source Type: research