A clinical, biologic and mechanistic analysis of the role of ZNF692 in cervical cancer.

CONCLUSION: ZNF692 promotes CC cells proliferation and invasion through suppressing p27kip1 transcription by directly binding its promoter region, which suggests that ZNF692 may serve as an underlying therapeutic target and prognostic marker in CC. PMID: 30466806 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30466806?dopt=Abstract

Source: Gynecologic Oncology - November 19, 2018 Category: Cancer & Oncology Authors: Zhu B, Pan Y, Zheng X, Zhang Q, Wu Y, Luo J, Li Q, Lu E, Xu L, Jin G, Ren B Tags: Gynecol Oncol Source Type: research