Involvement of GPx4-regulated lipid peroxidation in IPF pathogenesis.

Conclusion: These findings suggest that GPx4 expression levels were reduced in IPF and GPx4-regulated lipid peroxidation can be involved in IPF pathogenesis via modulating TGF-b-induced myofibroblast differentiation.

http://erj.ersjournals.com/cgi/content/short/52/suppl_62/OA5351?rss=1

Source: European Respiratory Journal - November 19, 2018 Category: Respiratory Medicine Authors: Tsubouchi, K., Araya, J., Minagawa, S., Hara, H., Hosaka, Y., Ichikawa, A., Saito, N., Yoshida, M., Ishikawa, T., Numata, T., Kaneko, Y., Nakayama, K., Kuwano, K. Tags: Mechanisms of Lung Injury and Repair Source Type: research

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