Monocytes and dendritic cells with hyperinflammatory profile in lungs of sarcoidosis patients

Conclusion: Monocytes and DCs in lungs of sarcoidosis patients showed altered frequencies compared to healthy controls and exhibited an inflammatory phenotype with spontaneous, high TNF production particularly in non-LS patients, possibly contributing to the chronic course of the disease.

Source: European Respiratory Journal - November 19, 2018 Category: Respiratory Medicine Authors: Lepzien, R., Liu, S., Kullberg, S., Eklund, A., Grunewald, J., Smed-Sörensen, A. Tags: Sarcoidosis and other granulomatous ILD/DPLD Source Type: research