FRAX ® based intervention thresholds for management of osteoporosis in Singaporean women

ConclusionThe ITs for osteoporosis treatment in Singapore show marked variations across ethnicities. Weighted mean thresholds may overcome the dilemma of intervening at different thresholds for different ethnicities. Choosing fixed ITs may have to involve trade-offs between sensitivity and specificity. FRAX ®-based age-dependent or the fixed intervention thresholds suggested as an alternative to be considered for use in Singapore though further studies on the societal and health economic impacts of choosing these thresholds in Singapore are needed.
Source: Archives of Orthopaedic and Trauma Surgery - Category: Orthopaedics Source Type: research