Cardiology MCQ 380: Bivalirudin

Bivalirudin a) Bivalirudin is a synthetic 20 amino acid polypeptide b) Inactivates both free and fibrin bound thrombin c) Useful in HITS d) All of the above ["Click here for the answer with explanation", "Correct Answer:"] d) All of the above Bivalirudin is a synthetic 20 amino acid polypeptide – interacts bivalently with both active catalytic site and exosite 1 of thrombin. Inactivates both free and fibrin bound thrombin Short half life of 25 minutes – confers a potential safety advantage Half life may be increased in renal failure Useful in HITS (Heparin Induced Thrombocytopenia Syndrome) ISAR-REACT 3, REPLACE-2, ACUITY and HORIZONS-AMI Trials have shown the efficacy of Bivalirudin. The post Cardiology MCQ 380: Bivalirudin appeared first on Cardiophile MD.
Source: Cardiophile MD - Category: Cardiology Authors: Tags: Cardiology MCQ DM / DNB Cardiology Entrance Source Type: blogs