The Use of Post-ablation Stimulated Thyroglobulin in Predicting Clinical Outcomes in Differentiated Thyroid Carcinoma – What Cut-off Values Should We Use?

Recently published international guidelines recommended using the stimulated thyroglobulin (sTg) post-radioactive iodine (RAI) ablation, in conjunction with tumour stage, as a risk stratification factor. The choice of cut-off values for sTg, namely 1 and 10 ng/ml, was, however, largely based on the functional sensitivities of the assays used, with relatively few published data addressing the prognostic impact of alternative cut-off values. Our study aims to provide data on the prognostic value of sTg at different levels of sensitivities and specificities.

Source: Clinical Oncology - November 16, 2018 Category: Radiology Authors: K.C.W. Wong, T.Y. Ng, K.S. Yu, J.S.S. Kwok, K.C.A. Chan, J.J.S. Suen, S.F. Leung, A.T.C. Chan Tags: Original Article Source Type: research