Therapeutic targeting potential of chromatin-associated proteins in MLL -rearranged acute leukemia

ConclusionsHere, we review chromatin-associated proteins fundamental toMLLr AL development, highlighting those with targeting potential by small molecule inhibitors. In particular, we focus on synthetic targeting of multiple chromatin-associated proteins, a strategy that shows superior therapeutic efficacy and offers hope for overcoming drug resistance.
Source: Cellular Oncology - Category: Cancer & Oncology Source Type: research