Efficacy of non-pharmacological interventions for procedural pain relief in adults undergoing burn wound care: A systematic review and meta-analysis of randomized controlled trials

Publication date: November 2018Source: Burns, Volume 44, Issue 7Author(s): Michael Scheffler, Susan Koranyi, Winfried Meissner, Bernhard Strauß, Jenny RosendahlAbstractThe aim of the present meta-analysis was to investigate the efficacy of non-pharmacological interventions for procedural pain relief in adults undergoing burn wound care compared to standard care alone or an attention control.Through a comprehensive literature search in various electronic databases 21 eligible randomized controlled trials (RCTs) were included, comprising a total of 660 patients. Random effects meta-analyses revealed significant positive treatment effects on pain outcomes, Hedges’ g = 0.58, 95% CI [0.33; 0.84]. Heterogeneity of study effects was substantial, I2 = 72%. Effects were significantly larger for comparisons against treatment as usual (TAU), g = 0.69, CI 95% [0.40; 0.98] than for comparisons against attention control groups, g = 0.21 [−0.11; 0.54], p < 0.001. Distraction interventions, particularly those using virtual reality, and hypnosis revealed the largest effects on pain relief. Non-pharmacological interventions further resulted in a significant small, homogeneous effect on anxiety reduction, g = 0.36 [0.20; 0.52].In summary, benefits of non-pharmacological interventions on procedural pain relief and reduction of mental distress were demonstrated. Results have been proven to be free of publication bias. However, f...
Source: Burns - Category: Dermatology Source Type: research