A 10-second ECG-based Root Mean Square of Successive Differences is a valid and reliable measure of heart rate variability

We thank Lombardi et al.1for highlighting the relevance of our paper2 in their editorial comment, but strongly disagree with their conclusion that the results of our study based on short-term heart rate variability (HRV) are “difficult to interpret”. We initially shared the same skepticism and concerns regarding the utility of ultra-short HRV measurements based on 10-second ECGs, which is why we set out to extensively test this in a validation study3 prior to using 10-second Root Mean Square of Successive Difference s (RMSSD) in our recent publication2.

Source: Heart Rhythm - November 1, 2018 Category: Cardiology Authors: Balewgizie Sileshi Tegegne, Tengfei Man, Arie M. van Roon, Harri ëtte Riese, Harold Snieder Source Type: research