Parameter subset selection techniques for problems in mathematical biology.

This study demonstrates that methods based on local sensitivities are preferable in terms of computational cost and model fit when good initial parameter values are available, but that global methods should be considered when initial parameter value is not known or poorly understood. For global sensitivity analysis, Morris screening provides results in terms of parameter sensitivity ranking at a much lower computational cost.
PMID: 30377765 [PubMed - as supplied by publisher]

Source: Biological Cybernetics - October 30, 2018 Category: Science Authors: Olsen CH, Ottesen JT, Smith RC, Olufsen MS Tags: Biol Cybern Source Type: research