Clinical correlates of subsyndromal depression in African American individuals with psychosis: The relationship with positive symptoms and comorbid substance dependence
Patients with psychosis exhibit subsyndromal depressive symptoms during the course of illness and yet the clinical correlates of these symptoms remain under-investigated. We aimed to investigate the clinical correlates of subsyndromal depression in psychosis including the extent to which they mediate commonly observed comorbid substance dependence. We developed a model of depression in a non-clinical sample recruited via Amazon's Mechanical Turk (N = 266), and confirmed that model in a locally recruited African-American clinical sample comprising psychotic and non-psychotic individuals (N = 256).
Source: Schizophrenia Research - Category: Psychiatry Authors: Emma E.M. Knowles, Samuel R. Mathias, Godfrey D. Pearlson, Jennifer Barrett, Josephine Mollon, Dominique Denbow, Katrina Aberzik, Molly Zatony, David C. Glahn Source Type: research