Prenatal 25-hydroxyvitamin D deficiency affects development of atopic dermatitis via DNA methylation

Due to the hypomethylation and consequently increased expression of oxidative stress-promoting genes in severely vitamin D-deficient fetus, the resulting offspring is predisposed to subsequent AD development and its severity.

Source: Journal of Allergy and Clinical Immunology - October 20, 2018 Category: Allergy & Immunology Authors: Hyun-Ju Cho, Youn Ho Sheen, Mi-Jin Kang, Seung-Hwa Lee, So-Yeon Lee, Jisun Yoon, Sungsu Jung, Si Hyeon Lee, Young-Ho Kim, Song-I. Yang, Eun Lee, Ju-Hee Seo, Kangmo Ahn, Kyung Won Kim, Dong In Suh, Hye-Sung Won, Mi-Young Lee, Soo Hyun Kim, Suk-Joo Choi, Ja Source Type: research