A ratiometric fluorescent probe for bioimaging and biosensing of HBrO in mitochondria upon oxidative stress.

A ratiometric fluorescent probe for bioimaging and biosensing of HBrO in mitochondria upon oxidative stress.
Chem Commun (Camb). 2018 Oct 11;:
Authors: Huang H, Tian Y
Abstract
A novel ratiometric fluorescent probe with high selectivity and sensitivity was designed and developed for bioimaging and biosensing of HBrO in mitochondria. Using this useful tool with low cytotoxicity and good biocompatibility, it was found that O2˙--induced oxidative stress triggered the burst of HBrO in mitochondria.
PMID: 30306159 [PubMed - as supplied by publisher]

Source: Chemical Communications - October 11, 2018 Category: Chemistry Authors: Huang H, Tian Y Tags: Chem Commun (Camb) Source Type: research