Short-term physiological hypoxia potentiates the therapeutic function of mesenchymal stem cells

In the bone marrow, MSCs reside in a hypoxic milieu (1 –5% O2) that is thought to preserve their multipotent state. Typically, in vitro expansion of MSCs is performed under normoxia (~ 21% O2), a process that has ...

Source: Stem Cell Research and Therapy - October 11, 2018 Category: Stem Cells Authors: Ben Antebi, Luis A Rodriguez II, Kerfoot P Walker III, Amber M Asher, Robin M Kamucheka, Lucero Alvarado, Arezoo Mohammadipoor and Leopoldo C Cancio Tags: Research Source Type: research