Fluorinated triazole-containing sphingosine analogues. Syntheses and in vitro evaluation as SPHK inhibitors

Org. Biomol. Chem., 2018,16,7230-7235 DOI: 10.1039/C8OB01867G, PaperMargarita Escudero-Casao, Adri à Cardona, Raúl Beltrán-Debón, Yolanda Díaz, M. Isabel Matheu, Sergio Castillón Fluorinated triazole-containing sphingosine analogues as SPHK inhibitors were synthesized from a common alkynyl aziridine key synthonvia enantioselective organocatalyzed aziridination. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research