e-HCL-32: a useful, valid and user friendly tool in the screening of bipolar II disorder

Bipolar type II (BDII) is a frequent disorder with high morbidity and mortality, characterized by depressive and hypomanic episodes. Early diagnosis can be effective in improving long-term prognosis. However, diagnosing BDII is challenging due to the difficulty in detecting past hypomanic episodes. The HCL-32 is a widely used and reliable screening instrument for the detection of past hypomanic episodes. Making this tool available to more patients could help diagnose and treat undetected cases of BDII earlier.
Source: Comprehensive Psychiatry - Category: Psychiatry Authors: Source Type: research

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This study included 243 youths, ages 12 to 25 years (42 healthy controls, 43 non–help-seeking individuals [stage 0], 52 help-seeking youth experiencing distress and possibly mild symptoms of anxiety or depression [stage1a], and 108 youth demonstrating attenuated symptoms of an SMI such as bipolar disorder or psychosis [stage 1b]). Participants completed an adapted version of the Childhood Trauma and Abuse scale. There were high frequencies of reported trauma across all stages. Symptomatic individuals experienced more trauma and bullying. Stage 1b individuals reported more physical abuse. Stage 1b also indicated psych...
Source: The Journal of Nervous and Mental Disease - Category: Psychiatry Tags: Original Articles Source Type: research
To investigate which factors individuals with a psychotic depression experience as preventive of suicide while beeing hospitalized. Semi-structured qualitative interviews with nine inpatients, all hospitalized for a unipolar or bipolar depressive episode w...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Suicide and Self-Harm Source Type: news
Publication date: 12 December 2019Source: Cell, Volume 179, Issue 7Author(s): Cross-Disorder Group of the Psychiatric Genomics ConsortiumSummaryGenetic influences on psychiatric disorders transcend diagnostic boundaries, suggesting substantial pleiotropy of contributing loci. However, the nature and mechanisms of these pleiotropic effects remain unclear. We performed analyses of 232,964 cases and 494,162 controls from genome-wide studies of anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, and Tourette synd...
Source: Cell - Category: Cytology Source Type: research
The D2 dopamine receptor and the serotonin 5-hydroxytryptamine 2A receptor (5-HT2A) are closely-related G-protein–coupled receptors (GPCRs) from the class A bioamine subfamily. Despite structural similarity, they respond to distinct ligands through distinct downstream pathways, whose dysregulation is linked to depression, bipolar disorder, addiction, and psychosis. They are important drug targets, and it is important to understand how their bias toward G-protein versus β-arrestin signaling pathways is regulated. Previously, evolution-based computational approaches, difference Evolutionary Trace and Evolutionary ...
Source: Journal of Biological Chemistry - Category: Chemistry Authors: Tags: Signal Transduction Source Type: research
In a 20-year study, most cognitive functions in 445 individuals with psychotic disorders declined, according to a report published inJAMA Psychiatry.“Compared with a matched control group, year-20 cognitive outcomes were poor in [participants with] psychotic disorders, especially for older participants,” wrote Anne-Kathrin J. Fett, Ph.D., of the University of London and colleagues. “These results provide the first comprehensive picture of long-term cognitive changes and associated clinical and functional outcomes in psychotic disorders.”The participants were part of the Suffolk County Mental Health ...
Source: Psychiatr News - Category: Psychiatry Tags: Anne-Kathrin J. Fett cognitive decline Ph.D. psychotic disorders Suffolk County Mental Health Project Source Type: research
For many participants, Medicaid — the program that provides health care to millions of low-income Americans — isn’t free. It’s a loan. And the government expects to be repaid. Are you surprised to hear that? So was today’s guest. Rachel Corbett recently wrote an article explaining in what circumstances you could be at risk. Join us to find out if this could happen to you, how you can protect yourself and what is next for the healthcare program. SUBSCRIBE &REVIEW Guest information for ‘Rachel Corbett Medicaid’ Podcast Episode Rachel Corbett is the author of You Must Change Y...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Aging General Health-related Interview Mental Health and Wellness Podcast Policy and Advocacy The Psych Central Show Treatment Source Type: blogs
Publication date: Available online 10 December 2019Source: Journal of Psychiatric ResearchAuthor(s): Madhukar H. Trivedi, Cherise Chin Fatt, Manish K. Jha, Crystal M. Cooper, Joseph M. Trombello, Brittany L. Mason, Jennifer Hughes, Bharathi S. Gadad, Andrew H. Czysz, Russell T. Toll, Anne K. Fuller, Sangita Sethuram, Taryn L. Mayes, Abu Minhajuddin, Thomas Carmody, Tracy L. GreerAbstract:Depression has a chronic and recurrent course often with early onset and is the leading cause of disability worldwide. In contrast to diagnoses for other conditions which rely on precise medical tests, the diagnosis of depression still foc...
Source: Journal of Psychiatric Research - Category: Psychiatry Source Type: research
CONCLUSION: There is positive but nonconclusive evidence that adjunctive light therapy reduces symptoms of bipolar depression and increases clinical response. Light therapy is well tolerated with no increased risk of affective switch. PMID: 31826657 [PubMed - as supplied by publisher]
Source: Canadian Journal of Psychiatry - Category: Psychiatry Authors: Tags: Can J Psychiatry Source Type: research
More than 80 years after its introduction, electroconvulsive therapy (ECT) remains the most effective treatment for both unipolar and bipolar depression, with response rates of approximately 75% and remission rates of greater than 50%(1). While the general depiction of ECT in movies and television continues to be of painful and traumatic treatments(2), the FDA recognized the overall safety of ECT devices by reclassifying them as Class II in December 2018. Mandated among the labeling requirements was warnings about the potential for physical trauma including fractures.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - Category: Neurology Authors: Source Type: research
Opioids are a group of very strong pain relievers used to relieve pain after a surgery or traumatic injury. They are much more effective than over-the-counter pain relievers, however, they are also highly addictive. People who suffer from mental health conditions are much more likely to become addicted to opioids, making it important to understand the link between opioids and mental health. The Connection Between Addiction to Opioids and Mental Health People with mood and anxiety disorders are twice as likely to use opioids as people without mental health disorders They are also more than three times as likely to misuse ...
Source: Cliffside Malibu - Category: Addiction Authors: Tags: Addiction Addiction to Pharmaceuticals Mental Health mental health costs mental health coverage mental illness opiate addiction opiates opioid opioid crisis opioids Source Type: blogs
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