The effect of phosphodiesterase-5 inhibitor, tadalafil, on in vitro potassium chloride-induced contractions of isolated human ureteral tissue

Conclusion: Tadalafil reduces KCl-induced contractions of isolated human ureteral tissue in vitro. No incremental relaxations in contractions occurred by increasing the dose of tadalafil from 20 μM to 40 μM.

Source: Indian Journal of Urology - October 1, 2018 Category: Urology & Nephrology Authors: MS Sakthivel Ratna Prabha Onkar Singh Nitin S Kekre Santosh Kumar Source Type: research