Herpes Zoster Oticus, Ophthalmicus, and Cutaneous Disseminated: Case Report and Literature Review

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Source: Neuro-Ophthalmology - Category: Opthalmology Authors: Source Type: research

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T. Goyal and I. Ali
Source: Emerging Infectious Diseases Journal - Category: Infectious Diseases Source Type: research
Since September, four infants in New York City have contracted herpes linked to the metzitzah b'peh ceremony, in which a Jewish clergyman uses his mouth to remove blood from the incision.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Results from the Solana HSV 1+2/VZV assay for the detection of herpes simplex virus 1 (HSV-1), HSV-2, and varicella-zoster virus (VZV) in cutaneous or mucocutaneous specimens were compared with that of viral culture and a commercial PCR assay (RealStar alpha herpesvirus PCR kit). Three hundred two mucocutaneous specimens, for which HSV-1, HSV-2, or VZV viral culture or PCR detection have been requested, were randomly selected and prospectively processed on the Solana assay and viral culture or the RealStar assay. Discordant results between culture and the Solana assay were further analyzed using the RealStar assay. A Bayes...
Source: Journal of Clinical Microbiology - Category: Microbiology Authors: Tags: Virology Source Type: research
Publication date: Available online 22 February 2020Source: Multiple Sclerosis and Related DisordersAuthor(s): Mohammad Hossein Harirchian, Maryam Poursadeghfard, Alireza Sadeghipour, Hoda Kamali, Payam SarrafAbstractFingolimod has been the first approved oral medication in MS for its relapsing remitting type. It is a non-selective sphingosine1-phosphate (S1P) receptor modulator on lymphocytes. Engagement of this receptor blocks the T cells and B cells migration from the lymph nodes into the inflamed central nervous system (CNS) via bloodstream. In spite of this known immunomodulatory mechanism, there are some reports about...
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research
Conclusion: These data suggest that the diagnosis of acute retinal necrosis can be reasonably inferred on clinical examination, providing a guide for initial empiric therapy.
Source: RETINA - Category: Opthalmology Tags: Original Study Source Type: research
Publication date: Available online 20 February 2020Source: IDCasesAuthor(s): Catherine Brahe, Rachel EllisAbstractLate diagnosis of HIV is associated with increased morbidity and mortality. Infected individuals need to be identified early and started on antiretroviral therapy to increase their survival and to limit transmission to the community. Historically speaking, late diagnosis has been a common occurrence in the United States, despite the majority of those patients having had a medical encounter in the year prior to their diagnosis. These visits represent missed opportunities for HIV testing and therefore delays in i...
Source: IDCases - Category: Infectious Diseases Source Type: research
ConclusionOur results showed that JZ-1 protects against HSV-2 infection, and this beneficial effect may be mediated by inducing autophagy via inhibition of the PI3K/Akt/mTOR signaling axis.Graphical abstract
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
The P2X7 receptor (P2X7R) is an ATP-gated ion channel known for its proinflammatory activity. Despite its participation in host defense against pathogens, the role played in viral infections, notably those caused by herpes viruses, has been seldom studied. Here we investigated the effect of P2X7R expression on human herpes virus 6 A (HHV-6A) infection of P2X7R-expressing HEK293 cells. We show that functional P2X7R increases while its blockade decreases viral load. Interestingly, HHV-6A infection was enhanced in HEK293 cells transfected with P2X7R cDNA bearing the gain of function 489C>T SNP (rs208294, replacing a histid...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
To compare the efficacies between intratumoral herpes simplex virus-thymidine kinase (HSV-TK)/ganciclovir (GCV) gene therapy and oncolytic virotherapy for image-guided radiofrequency hyperthermia (RFH)-enhanced treatment of orthotopic liver cancer.
Source: Journal of Vascular and Interventional Radiology : JVIR - Category: Radiology Authors: Tags: Scientific Traditional Poster Source Type: research
Torphy DE, Ray CG, McAlister R, Du JN. Herpes simplex virus infection in infants: A spectrum of disease. J Pediatr 1970;76:405-8 and Charnock EL, Cramblett HG. 5-Iodo-2 ′-deoxyuridine in neonatal herpesvirus hominis encephalitis. J Pediatr 1970;76:459-63.
Source: The Journal of Pediatrics - Category: Pediatrics Authors: Source Type: research
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