RETRACTED ARTICLE: The BRCA2 variant c.68-7 T & gt;A is associated with breast cancer

ConclusionBRCA2 c.68-7T>A is associated with breast cancer. In the families selected due to aggregation of breast cancer, carriers of theBRCA2 c.68-7T>A variant have increased risk for breast cancer. It is, however, possible that the variant has lower penetrance than the average pathogenicBRCA2 variants, and that in the families selected for having known aggregation of breast cancer other (modifying) factors contributed to the observed results.
Source: Hereditary Cancer in Clinical Practice - Category: Cancer & Oncology Source Type: research