Frequency of BRCA1 and BRCA2 causative founder variants in ovarian cancer patients in South-East Poland

ConclusionsThe frequency of 13 causative founder variants in Podkarpacie was lower than in other regions of Poland. Testing of threeBRCA1 mutations (c.5266dupC, c.181  T >  G, c.676delT) should be considered a sensitive test panel.
Source: Hereditary Cancer in Clinical Practice - Category: Cancer & Oncology Source Type: research