Growth hormone and Insulin-like growth factor-I (IGF-I) modulate the expression of L-type amino acid transporters in the muscles of spontaneous dwarf rats and L6 and C2C12 myocytes.

CONCLUSIONS: IGF-I increased LAT1 mRNA level in myocytes. However, the role of LAT1 in IGF-I-induced mTORC1 activation and cell functions remains unclear.
PMID: 30273774 [PubMed - as supplied by publisher]

Source: Growth Hormone and IGF Research - September 23, 2018 Category: Endocrinology Authors: Sawa R, Nishida H, Yamamoto Y, Wake I, Kai N, Kikkawa U, Okimura Y Tags: Growth Horm IGF Res Source Type: research