Estradiol vaginal inserts (4 µg and 10 µg) for treating moderate to severe vulvar and vaginal atrophy: a review of phase 3 safety, efficacy and pharmacokinetic data.

CONCLUSIONS: The recently FDA-approved E2 softgel vaginal insert (4 µg and 10 µg) was safe and effective over 12 weeks for treating moderate to severe dyspareunia due to menopausal VVA with minimal systemic E2 levels.
PMID: 30238814 [PubMed - as supplied by publisher]

Source: Current Medical Research and Opinion - September 23, 2018 Category: Research Tags: Curr Med Res Opin Source Type: research