Ischiocrural Strength May Be a Better Prognostic Marker Than Quadriceps Strength in COPD

We present the results of a retrospective study with longitudinal follow-up of 60 patients with severe COPD followed for 7  years. During follow-up 22 patients died, mainly of respiratory cause. We have observed that the strength of knee flexor muscles (ischiocrural) and dominant handgrip were independent predictors of mortality in severe COPD patients. However, knee extensor strength (quadriceps) was not an independen t predictor of mortality. This is the first study which highlights the importance of knee flexor musculature as a prognostic factor in COPD.
Source: Lung - Category: Respiratory Medicine Source Type: research