The appliances and prospects of aurum nanomaterials in biodiagnostics, imaging, drug delivery and combination therapy

Publication date: Available online 14 September 2018Source: Asian Journal of Pharmaceutical SciencesAuthor(s): Dan Yang, Feiyang Deng, Dechun Liu, Bo He, Bing He, Xing Tang, Qiang ZhangAbstractAurum nanomaterials (ANM), combining the features of nanotechnology and metal elements, have demonstrated enormous potential and aroused great attention on biomedical applications over the past few decades. Particularly, their advantages, such as controllable particle size, flexible surface modification, higher drug loading, good stability and biocompatibility, especially unique optical properties, promote the development of ANM in biomedical field. In this review, we will discuss the advanced preparation process of ANM and summarize their recent applications as well as their prospects in diagnosis and therapy. Besides, multi-functional ANM-based theranostic nanosystems will be introduced in details, including radiotherapy (RT), photothermal therapy (PTT), photodynamic therapy (PDT), immunotherapy (IT), and so on.Graphical abstract Gold nanomaterials could be prepared via various methods and applied in drug delivery, imaging, biodiagnostics as well as an excellent theranostics platform.
Source: Asian Journal of Pharmaceutical Sciences - Category: Drugs & Pharmacology Source Type: research