A Case of a Small Cell Lung Cancer Patient with Anti-transcriptional Intermediary Factor 1 γ Antibody Who Developed Dermatomyositis after Successful Chemoradiotherapy.

A Case of a Small Cell Lung Cancer Patient with Anti-transcriptional Intermediary Factor 1γ Antibody Who Developed Dermatomyositis after Successful Chemoradiotherapy. Intern Med. 2018 Sep 12;: Authors: Aritomi T, Kido T, Nakano K, Satoh Y, Noguchi S, Jotatsu T, Hanaka T, Satoh M, Tanaka Y, Yatera K Abstract We herein report a 63-year-old woman with small-cell lung cancer (SCLC) who developed dermatomyositis (DM) after initial chemoradiotherapy despite tumor reduction. Serum anti-TIF1γ antibody was detected before the development of DM, and its levels increased over time. She died five months after the diagnosis of SCLC. Anti-TIF1γ antibody is known to be a marker for cancer-associated DM (CAM); however, the present case indicates that the antibody can be found in cancer patients without DM. This case is also unusual, as DM developed later despite successful chemoradiotherapy. (86 words <100). PMID: 30210109 [PubMed - as supplied by publisher]
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research