Congenital myasthenic syndromes and myasthenia

A 38-year-old woman was referred to our hospital for an incidental thymic cyst. The chest CT demonstrated a 7cm sized cystic and mass lesion in the anterior mediastinum. She had no symptoms of myasthenia gravis(MG). The tumor was completely resected by thymectomy. Histological examination of the tumor identified it as a thymic cyst with fibrous tissue, cystic structure, cholesterol clefts, calcification, necrotic material, and chronic inflammatory lymphohistiocytic infiltrate. Two months after the surgery, she experienced post-thymectomy generalized MG.
Source: Neuromuscular Disorders - Category: Neurology Authors: Source Type: research