Sma clinical data, outcome measures and registries

This study explored the utility of ACTIVE scaled workspace volume scores to quantify meaningful change in individuals with spinal muscular atrophy (SMA) due to disease progression or treatment. ACTIVE, a 65-second custom designed video game, uses a skeletal tracking algorithm to quantify the volume of space (m3) the player can interact with while reaching in three dimensions to squish spiders or dig for jewels. Sixty-two individuals with SMA type 2 or 3 (age 10.5y +/-5y) and 362 age-matched controls (age 10.7y +/-3.5y) participated.

Source: Neuromuscular Disorders - September 6, 2018 Category: Neurology Authors: L. Alfano, N. Miller, M. Iammarino, M. Moore-Clingenpeel, S. Lowes, M. Dugan, M. Waldrop, K. Flanigan, G. Noritz, C. Tsao, S. Al Zaidy, J. Kissel, L. Lowes Source Type: research