India's oxytocin ban delayed by a month as Delhi HC hears cases against it
Oxytocin is a hormone drug used to induce labour in pregnant women and stall post-partum bleeding.
Gil, Luc ía / Mínguez, Ignacio / Caffesse, Raul / Llambés, FernandoPage 69 - 73Purpose: To determine the influence of plaque and progesterone on periodontitis in pregnant women and their relationship with inflammatory mediators.Materials and Methods: A longitudinal observational study of 60 pregnant women was undertaken in two observation periods. During the third trimester, plaque Index (PI), bleeding on probing (BOP), probing pocket depth (PPD), and clinical attachment level (CAL) were assessed, and the basal levels of progesterone, CRP, IL-6 and TNF- α in plasma were measured. The second obser...
Partial quantitative deficiency of plasma von Willebrand factor (VWF) is responsible for the majority of cases of von Willebrand disease (VWD), the most common inherited human bleeding disorder. International consensus guidelines recommend that patients with reduced plasma VWF antigen (VWF:Ag) levels and bleeding phenotypes be considered in 2 distinct subsets. First, patients with marked reductions in plasma VWF levels (
Congenital factor VII deficiency is a rare autosomal recessive disorder associated to different haemorrhagic manifestations. Labour and delivery may cause bleeding risk in patients with this coagulation deficit, thus it is appropriate to clarify whether prophylaxis of peripartum haemorrhage is necessary. To date, there are very few cases in scientific literature which report the management of women with congenital factor VII deficiency during labour, and a consensus for prophylaxis does not exist.
This study aimed to determine the incidence of severe ITP in pregnancy in the United Kingdom, as well as current management strategies and maternal and fetal outcomes.
(N Engl J Med. 2018;379:1562–1570) A 36-year-old pregnant woman was evaluated at 33 weeks gestation because of newly diagnosed adenocarcinoma. At 32 weeks’ admission, the patient had presented to another hospital with a history of 3 days of nonradiating, severe pain accompanied by nausea in her lower back that rated 10 on a scale of 10 and originated in the epigastric region and migrated to the upper right quadrant and lower back. On examination, there was tenderness in the right upper quadrant. The gravid uterus was soft, and no abnormal fetal findings were observed. An incidental finding of renal ultrasonogr...
Introduction: Ectopic pregnancy (EP) is defined as the extrauterine implantation of the blastocyst and has an incidence rate of 1.3 –2.4%. Bleeding associated with EP is the main cause of maternal death in the first trimester of pregnancy.
Introduction: An ectopic pregnancy occurs when a fertilised egg implants outside the uterine cavity, mostly in one of the Fallopian tubes. In the developed countries, between 1% and 2% of all reported pregnancies are extrauterine gravidities. The classic clinical triad of ectopic pregnancy is pain, amenorrhea, and vaginal bleeding; however, only about 50% of patients present with all 3 symptoms. Ectopic pregnancy is common in women of reproductive age, therefore its treatment requires special attention and ideal management strategies.
Introduction: As anticoagulants increase the risks of bleeding during delivery and epidural puncture consecutive to neuraxial anaesthesia, women with anticoagulation during pregnancy can be offered a planned delivery with a therapeutic window of anticoagulation.
Introduction: A venous sinus thrombosis is a thrombotic occlusion of the cerebral venous drainage. Patients present with unspecific symptoms such as headache, vision disturbances, or altered consciousness. Complications include intracerebral bleeding and/or increased intracranial pressure leading to poor neurological outcome. Besides clotting disorders, pregnancy and puerperium constitute risk factors for this rare condition. Roughly 0.004 –0.01% of pregnancies are complicated by cerebral venous sinus thrombosis (CVST).
Introduction: 45 year old lady, Para 2+2, background history of hypercholesterolemia and pancreatitis, presented to the ED with left sided pain, shoulder tip pain and amenorrhea for four weeks, and positive pregnancy test. Gynaecology team took over her care to investigate for an ectopic pregnancy. The serum beta Hcg was 2206mU/L, however, pelvic US showed an empty uterus with large amount of free fluid consistent with hemoperitoneum. She was taken for a diagnostic laparoscopy. Intraoperative findings included normal ovaries and tubes with no bleeding or hyperemia but spleen appeared large and inflamed with capsular rupture.