Dysregulation of the expression of antimicrobial peptides in patients with cutaneous T-cell lymphoma

Cutaneous T-cell lymphoma (CTCL) patients typically present with skin lesions, that seem inflammatory and in the initial disease stages are commonly mistaken for an inflammatory skin disease such as eczema or psoriasis. For inflammatory conditions like psoriasis it has been shown, that the expression of antimicrobial peptides (AMP) in lesional skin differs from healthy skin. With the present study we wanted to characterize the expression of AMPs in the skin of patients with CTCL.
Source: European Journal of Cancer - Category: Cancer & Oncology Authors: Source Type: research