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NYC Rats Are Even Grosser Than You Thought

Rats are a part of daily life in New York as they scurry about subway tracks and garbage heaps. However, even though the creatures been neighbors of New Yorkers for centuries, researchers are still learning exactly how these rodents could affect the health of millions. In a recently released study from scientists at Columbia University, researchers confirmed the fears of every New Yorker. These ubiquitous pests are housing dangerous bacteria including E. Coli, Salmonella and viruses including the deadly Seoul Hantavirus.
Source: ABC News: Health - Category: Consumer Health News Tags: Health Source Type: news

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AbstractAvian pathogenicE. coli (APEC) is the etiologic agent of avian colibacillosis, the most common disease responsible for chicken morbidity in the world. Although multiple virulence-associated factors were identified, their prevalence in Algeria is still poorly known. In the present research, 92 avian pathogenicE. coli (APEC) isolates were recovered from broilers with clinical signs and lesions of colibacillosis. In addition, 32E. coli isolates collected from feces of healthy birds (AFEC) were included for comparison. All isolates were investigated by PCR for the presence of a total of 11 virulence-associated genes de...
Source: Tropical Animal Health and Production - Category: Veterinary Research Source Type: research
This article is protected by copyright. All rights reserved
Source: Biotechnology and Bioengineering - Category: Biomedical Science Authors: Tags: Article Source Type: research
Biofilms are widely present in many human chronic infections, often more resistant to treatment with antibiotics. Bacterial diguanylate cyclases (DGCs) synthesize cyclic dimeric guanosine monophosphate (c-di-GMP) from two guanosine-5'-triphosphate (GTP) molecules. c-di-GMP is a central second messenger controlling biofilm formation, turning this class of enzymes an attractive target to prevent and disrupt biofilms of pathogenic bacteria. Here, we apply an in silico ligand- and target-based hybrid method to screen potential DGC inhibitors from an FDA-approved drug databank. Mass spectrometry assays confirmed that seven scre...
Source: Journal of the Brazilian Chemical Society - Category: Chemistry Source Type: research
A microscope that clips on to your phone's camera can detect bacteria, such as salmonella or E. coli, even in tiny amounts. But the technology can't yet distinguish between good and bad bacteria.(Image credit: Karen Brown/New England Public Radio)
Source: NPR Health and Science - Category: Consumer Health News Authors: Source Type: news
ConclusionTo the best of our knowledge, this is the first report showing production of nalidixic acid naturally by a strain of Streptomyces sp. Significance and Impact of the StudyIn this study, we isolated a strain of Streptomyces sp. producing nalidixic acid, which otherwise only obtained through chemical synthesis.This article is protected by copyright. All rights reserved.
Source: Journal of Applied Microbiology - Category: Microbiology Authors: Tags: Original Article Source Type: research
This article is protected by copyright. All rights reserved.
Source: Letters in Applied Microbiology - Category: Microbiology Authors: Tags: Original Article Source Type: research
ina G Abstract Urinary tract infections (UTIs) caused by uropathogenic Escherichia coli (UPEC) are among the most common infectious diseases in humans. Due to their frequent occurrence in the community and nosocomial settings, as well as the development of resistance to the commonly prescribed antimicrobial agents, an enormous financial burden is placed on healthcare systems around the world. Therefore, novel approaches to the prevention and treatment of UTIs are needed. Although UPEC may harbour a plethora of virulence factors, type I fimbriae and P pili are two of the most studied adhesive organelles, since the ...
Source: Acta Pharmaceutica - Category: Drugs & Pharmacology Authors: Tags: Acta Pharm Source Type: research
Publication date: April 2018 Source:Nano Energy, Volume 46 Author(s): Srinivaas Masimukku, Yu-Chen Hu, Zong-Hong Lin, Shuen-Wen Chan, Ting-Mao Chou, Jyh Ming Wu This work, we achieved the first-ever demonstration in the polydimethylsiloxane embedded with the abundant single-layer tungsten disulfide (WS2) nanoflowers (PDMS/WS2 NFs) for the degradation of organic dye (Rhodamine B, RB) in dark environment. The degradation ratio of the PDMS/WS2 NFs brick reached ~ 99% and achieved ten cycling test where each cycle took 90 min for the decomposition of the dye molecules. The rate constant of the PDMS embedded WS2 NFs was 0.13...
Source: Nano Energy - Category: Nanotechnology Source Type: research
Abstract Endosymbiotic interactions are frequently found in nature, especially in the group of protists. Even though many endosymbioses have been studied in detail, little is known about the mechanistic origins and physiological prerequisites of endosymbiont establishment. A logical step towards the development of endocytobiotic associations is evading digestion and escaping from the host's food vacuoles. Surface properties of bacteria are probably involved in these processes. Therefore, we chemically modified the surface of a transformant strain of Escherichia coli prior to feeding to Tetrahymena pyriformis. N‐(3‐dime...
Source: The Journal of Eukaryotic Microbiology - Category: Microbiology Authors: Tags: Original Article Source Type: research
Sonali Vadi, Vishal PeshattiwarIndian Journal of Critical Care Medicine 2018 22(2):116-118 Fondaparinux, a pentasaccharide administered for heparin-induced thrombocytopenia (HIT), can lead to the occurrence of thrombocytopenia. This patient underwent aortic stent graft placement for Salmonella paratyphi A-infected abdominal aortic aneurysm. Fondaparinux was administered for anticoagulation that led to a dramatic decline in his platelet counts. Investigations revealed HIT profile, PF4/heparin by particle gel immunoassay to be positive. Fondaparinux, a prescribed anticoagulant for HIT can paradoxically predispose to thrombocytopenia.
Source: Indian Journal of Critical Care Medicine - Category: Intensive Care Authors: Source Type: research
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