Disulfiram enhanced delivery of orally administered copper into the central nervous system in Menkes disease mouse model

ConclusionOur data demonstrated that disulfiram enhanced the delivery of orally administered copper into the central nervous system in MD model mice. The administration of disulfiram will enable patients to avoid unpleasant subcutaneous copper injection in the future.

http://link.springer.com/10.1007/s10545-018-0239-3

Source: Journal of Inherited Metabolic Disease - August 21, 2018 Category: Internal Medicine Source Type: research